Serine/threonine-protein phosphatase PP1 isozyme 4 (TOPP4), Recombinant Protein
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Serine/threonine-protein phosphatase PP1 isozyme 4 (TOPP4), Recombinant Protein

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Cat: RP04113
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Serine/threonine-protein phosphatase PP1 isozyme 4 (TOPP4)
Product Gene Name
TOPP4 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MATTTTTQGQ QTAIDSAVLD DIIRRLTEVR LARPGKQVQL SEAEIKQLCT TARDIFLQQP NLLELEAPIK ICGDIHGQYS DLLRLFEYGG FPPSANYLFL GDYVDRGKQS LETICLLLAY KIKYPGNFFL LRGNHECASI NRIYGFYDEC KRRFNVRVWK VFTDCFNCLP VAALIDDKIL CMHGGLSPDL DHLDEIRNLP RPTMIPDTGL LCDLLWSDPG KDVKGWGMND RGVSYTFGPD KVSEFLTKHD LDLVCRAHQV VEDGYEFFAD RQLVTVFSAP NYCGEFDNAG AMMSVDENLM CSFQILKPAE KKTKFMMSTK I
Sequence Positions
1-321, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
36,372 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Serine/threonine-protein phosphatase

NCBI/Uniprot Data

NCBI Accession #
NP_181514.1
NCBI GI #
15225576
NCBI GenBank Nucleotide #
NM_129543.3
NCBI GeneID
818571
NCBI Official Full Name
type one serine/threonine protein phosphatase 4
NCBI Official Symbol
TOPP4
NCBI Official Synonym Symbols
type one serine/threonine protein phosphatase 4
NCBI Protein Information
type one serine/threonine protein phosphatase 4
NCBI Summary
Encodes the catalytic subunit of a Type 1 phosphoprotein Ser/Thr phosphatase, expressed in roots, shoots and flowers.
UniProt Gene Name
TOPP4
UniProt Protein Name
Serine/threonine-protein phosphatase PP1 isozyme 4
UniProt Synonym Protein Names
Type one protein phosphatase 4
UniProt Primary Accession #
P48484
UniProt Secondary Accession #
Q147H5
UniProt Related Accession #
P48484
UniProt Comments
Serine/threonine-protein phosphatase that possesses phosphatase activity toward para-nitrophenyl phosphate (pNPP) in vitro (PubMed:21222654). Acts as positive regulator in the gibberellin (GA) signaling pathway to regulate plant growth and development. Promotes the GA-induced and proteasomal-dependent degradation of the DELLA proteins RGA and GAI by directly binding and dephosphorylating these proteins (PubMed:25010794). Involved in the regulation of phytochrome B (phyB) signaling pathway that controls photomorphogenesis. Promotes the proteasomal-dependent degradation of PIF5 factor by directly binding and dephosphorylating this protein (PubMed:26704640). Involved in the regulation of pavement cell (PC) interdigitation by modulating the auxin efflux carrier PIN1 polarity and endocytic trafficking. Regulates PIN1 polar targeting through direct binding and dephosphorylation. Acts antagonistically with PID in regulating PC development (PubMed:25560878).

For research use only, not for clinical use.