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Serine/threonine-protein phosphatase 5 (PAPP5), Recombinant Protein
Cat: RP06236
Size: 0.05 mg (Yeast)/ 0.2 mg (Yeast)/ 0.5 mg (Yeast)/ 1 mg (Yeast)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Serine/threonine-protein phosphatase 5 (PAPP5) , partial
Product Gene Name
PAPP5 recombinant protein
Product Synonym Gene Name
PAPP5
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
54,702 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Serine/threonine-protein phosphatase
NCBI/Uniprot Data
NCBI Accession #
NP_001031534.1
NCBI GI #
79324899
NCBI GenBank Nucleotide #
NM_001036457.3
NCBI GeneID
818881
NCBI Official Full Name
protein phosphatase 5.2
NCBI Official Symbol
PP5.2
NCBI Official Synonym Symbols
Arabidopsis thaliana protein phosphatase 5; AtPP5; F7D19.19; F7D19_19; PAPP5; Phytochrome-Associated Protein Phosphatase 5; PP5; PROTEIN PHOSPHATASE 5; protein phosphatase 5.2
NCBI Protein Information
protein phosphatase 5.2
NCBI Summary
Encodes a phytochrome-specific type 5 serine/threonine protein phosphatase. It dephosphorylates active Pfr-phytochromes. Controls light signal flux by enhancing phytochrome stability and affinity for a signal transducer. The gene is alternately spliced. This variant is an integral membrane protein localized to the ER and nuclear envelope. Belongs to one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808) with potential to interact with Hsp90/Hsp70 as co-chaperones. It also regulates tetrapyrrole biosynthesis through the accumulation of Mg-ProtoIX and acts as a negative regulator of photosynthesis associated nuclear gene expression during chloroplast biogenesis and development.
UniProt Gene Name
PAPP5
UniProt Synonym Gene Names
PP5
UniProt Protein Name
Serine/threonine-protein phosphatase 5
UniProt Primary Accession #
Q84XU2
UniProt Secondary Accession #
Q56X87; Q8RXU0; Q8W581; Q9SJH5
UniProt Related Accession #
Q84XU2
UniProt Comments
Isoform 2 dephosphorylates phosphorylated phytochromes, with a preference toward Pfr forms, and enhances phytochrome-mediated photoresponses, probably by enhancing their stability and their binding affinity for light signal transducers such as NDPK2. Can use para-nitrophenylphosphate (pNPP) as substrate.
For research use only, not for clinical use.