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Serine/threonine-protein kinase SRK2E (SRK2E), Recombinant Protein
Cat: RP04373
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Serine/threonine-protein kinase SRK2E (SRK2E)
Product Gene Name
SRK2E recombinant protein
Product Synonym Gene Name
SRK2E
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MDRPAVSGPM DLPIMHDSDR YELVKDIGSG NFGVARLMRD KQSNELVAVK YIERGEKIDE NVKREIINHR SLRHPNIVRF KEVILTPTHL AIVMEYASGG ELFERICNAG RFSEDEARFF FQQLISGVSY CHAMQVCHRD LKLENTLLDG SPAPRLKICD FGYSKSSVLH SQPKSTVGTP AYIAPEVLLK KEYDGKVADV WSCGVTLYVM LVGAYPFEDP EEPKNFRKTI HRILNVQYAI PDYVHISPEC RHLISRIFVA DPAKRISIPE IRNHEWFLKN LPADLMNDNT MTTQFDESDQ PGQSIEEIMQ IIAEATVPPA GTQNLNHYLT GSLDIDDDME EDLESDLDDL DIDSSGEIVY AM
Sequence Positions
1-362, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
38,506 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Serine/threonine-protein kinase
NCBI/Uniprot Data
NCBI Accession #
NP_567945.1
NCBI GI #
18418337
NCBI GenBank Nucleotide #
NM_119556.3
NCBI GeneID
829541
NCBI Official Full Name
Protein kinase superfamily protein
NCBI Official Symbol
OST1
NCBI Official Synonym Symbols
ATOST1; F17I5.140; F17I5_140; OPEN STOMATA 1; P44; SNF1-RELATED PROTEIN KINASE 2.6; SNRK2-6; SNRK2.6; SRK2E; SUCROSE NONFERMENTING 1-RELATED PROTEIN KINASE 2-6
NCBI Protein Information
Protein kinase superfamily protein
NCBI Summary
Encodes calcium-independent ABA-activated protein kinase, a member of SNF1-related protein kinases (SnRK2) whose activity is activated by ionic (salt) and non-ionic (mannitol) osmotic stress. Mutations disrupted ABA induction of stomatal closure as well as ABA inhibition of light-induced stomatal opening. However, regulation of stomatal opening/closing by light or CO(2) is not affected in these mutants. May act in the interval between ABA perception and reactive oxygen species production in the ABA signalling network.
UniProt Gene Name
SRK2E
UniProt Synonym Gene Names
OST1; SNRK2.6; SnRK2.6
UniProt Protein Name
Serine/threonine-protein kinase SRK2E
UniProt Synonym Protein Names
Protein OPEN STOMATA 1; SNF1-related kinase 2.6; SnRK2.6; Serine/threonine-protein kinase OST1
UniProt Primary Accession #
Q940H6
UniProt Secondary Accession #
O81763
UniProt Related Accession #
Q940H6
UniProt Comments
Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order to limit invaders, but actively reopened by bacteria after a few hours; virulent strains (e.g. Pst DC3000) are more efficient than avirulent strains (e.g. Pst DC3000 AvrRpt2) in reopening stomata. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1, and thus promotes stomata closure. Essential for stomatal closure in response to reactive oxygen species (ROS). Promotes MAPKKK18 activity upon abscisic acid (ABA) treatment (PubMed:26443375).
For research use only, not for clinical use.