Serine/threonine-protein kinase AtPK1/AtPK6 (ATPK1), Recombinant Protein
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Serine/threonine-protein kinase AtPK1/AtPK6 (ATPK1), Recombinant Protein

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Cat: RP04769
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6 (ATPK1)
Product Gene Name
ATPK1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MVSSQRPVPN KIQKQQYLSI SPSNSVLKDD VELEFSDVFG PLPEEANDIA YDEPAVVYSR SHSLVGPCSL DSHSLKLTKL TLLETEDSID LVECLEGESL KENDDFSGND DSDNEKALEG DLVKVSGVVG IDDFEVMKVV GKGAFGKVYQ VRKKETSEIY AMKVMRKDHI MEKNHAEYMK AERDILTKID HPFIVQLKYS FQTKYRLYLV LDFINGGHLF FQLYHQGLFR EDLARVYTAE IVSAVSHLHE KGIMHRDLKP ENILMDTDGH VMLTDFGLAK EFEENTRSNS MCGTTEYMAP EIVRGKGHDK AADWWSVGIL LYEMLTGKPP FLGSKGKIQQ KIVKDKIKLP QFLSNEAHAI LKGLLQKEPE RRLGSGLSGA EEIKQHKWFK GINWKKLEAR EVMPSFKPEV SGRQCIANFD KCWTDMSVLD SPASSPSSDP KANPFTNFTY VRPPPSFLHQ STTTL
Sequence Positions
1-465, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
52,588 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Serine/threonine-protein kinase

NCBI/Uniprot Data

NCBI Accession #
NP_001326081.1
NCBI GI #
1063710249
NCBI GenBank Nucleotide #
NM_001337768.1
NCBI GeneID
820020
NCBI Official Full Name
protein-serine kinase 1
NCBI Official Symbol
PK1
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA PROTEIN-SERINE KINASE 1; ARABIDOPSIS THALIANA PROTEIN-SERINE KINASE 6; ATPK1; ATPK6; ATS6K1; P70 RIBOSOMAL S6 KINASE; PK6; PROTEIN-SERINE KINASE; protein-serine kinase 1; ROTEIN-SERINE KINASE 6; S6K1
NCBI Protein Information
protein-serine kinase 1
NCBI Summary
Encodes a protein-serine kinase that phosphorylates ribosomal protein in vitro. Activation of AtS6k is regulated by 1-naphthylacetic acid and kinetin, at least in part, via a lipid kinase-dependent pathway. Involved in translational up-regulation of ribosomal proteins. Phosphorylated by PDK1. Interacts with RAPTOR1, which in turn interacts with TOR. SPK6 activity is affected by osmotic stress, and plants overexpressing S6k1 are hypersensitive to osmotic stress. The gene is expressed in all tissues examined, with highest expression level detected in metabolically active tissues.
UniProt Gene Name
ATPK1
UniProt Synonym Gene Names
ATPK6; S6K1
UniProt Protein Name
Serine/threonine-protein kinase AtPK1/AtPK6
UniProt Synonym Protein Names
Ribosomal-protein S6 kinase homolog 1
UniProt Primary Accession #
P42818
UniProt Secondary Accession #
Q8LFC1
UniProt Related Accession #
P42818; AAB33197
UniProt Comments
Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

For research use only, not for clinical use.