NCBI Accession #
NP_201205.1
NCBI GenBank Nucleotide #
NM_125796.5
NCBI Official Full Name
Inositol monophosphatase family protein
NCBI Official Symbol
SAL2
NCBI Official Synonym Symbols
ATSAL2; MBM17.10; MBM17_10
NCBI Protein Information
Inositol monophosphatase family protein
NCBI Summary
3'(2'),5'-bisphosphate nucleotidase
UniProt Synonym Gene Names
IPPase 2
UniProt Protein Name
SAL2 phosphatase
UniProt Synonym Protein Names
3'(2'),5'-bisphosphate nucleotidase 2 (EC:3.1.3.7); 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase 2; DPNPase 2; Inositol polyphosphate 1-phosphatase 2; IPPase 2; Inositol-1,4-bisphosphate 1-phosphatase 2 (EC:3.1.3.57)
UniProt Primary Accession #
O49623
UniProt Related Accession #
O49623
UniProt Comments
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS . Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation. Is also able to hydrolyze inositol 1,4-bisphosphate.