rRNA 2'-O-methyltransferase fibrillarin 2 (FIB2), Recombinant Protein
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rRNA 2'-O-methyltransferase fibrillarin 2 (FIB2), Recombinant Protein

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Cat: RP02117
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana rRNA 2'-O-methyltransferase fibrillarin 2 (FIB2)
Product Gene Name
FIB2 recombinant protein
Product Synonym Gene Name
FIB2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MRPPLTGSGG GFSGGRGRGG YSGGRGDGGF SGGRGGGGRG GGRGFSDRGG RGRGRGPPRG GARGGRGPAG RGGMKGGSKV IVEPHRHAGV FIAKGKEDAL VTKNLVPGEA VYNEKRISVQ NEDGTKTEYR VWNPFRSKLA AAILGGVDNI WIKPGAKVLY LGAASGTTVS HVSDLVGPEG CVYAVEFSHR SGRDLVNMAK KRTNVIPIIE DARHPAKYRM LVGMVDVIFS DVAQPDQARI LALNASYFLK SGGHFVISIK ANCIDSTVPA EAVFQTEVKK LQQEQFKPAE QVTLEPFERD HACVVGGYRM PKKPKAATAA
Sequence Positions
1-320, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
33,653 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_567724.1
NCBI GI #
18416588
NCBI GenBank Nucleotide #
NM_118695.4
NCBI GeneID
828668
NCBI Official Full Name
fibrillarin 2
NCBI Official Symbol
FIB2
NCBI Official Synonym Symbols
ATFIB2; fibrillarin 2; L73G19.10; L73G19_10
NCBI Protein Information
fibrillarin 2
NCBI Summary
encodes a fibrillarin, a key nucleolar protein in eukaryotes which associates with box C/D small nucleolar RNAs (snoRNAs) directing 2'-O-ribose methylation of the rRNA. This gene also encodes a novel box C/D snoRNA, U60.2f in its fifth intron that accumulates in seedlings and that their targeted residue on the 25 S rRNA is methylated.
UniProt Gene Name
MED36A
UniProt Synonym Gene Names
FIB2; FLP; MED36_1
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 36a
UniProt Synonym Protein Names
Fibrillarin-like protein 2; Histone-glutamine methyltransferase; rRNA 2'-O-methyltransferase fibrillarin 2 (EC:2.1.1.-)
UniProt Primary Accession #
Q94AH9
UniProt Secondary Accession #
Q9SZZ1
UniProt Related Accession #
Q94AH9
UniProt Comments
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.

For research use only, not for clinical use.