RNA polymerase II C-terminal domain phosphatase-like 2 (CPL2), Recombinant Protein
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RNA polymerase II C-terminal domain phosphatase-like 2 (CPL2), Recombinant Protein

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Cat: RP03118
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana RNA polymerase II C-terminal domain phosphatase-like 2 (CPL2) , partial
Product Gene Name
CPL2 recombinant protein
Product Synonym Gene Name
CPL2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
85,953 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
RNA polymerase II C-terminal domain phosphatase

NCBI/Uniprot Data

NCBI Accession #
NP_195747.2
NCBI GI #
79503115
NCBI GenBank Nucleotide #
NM_120205.5
NCBI GeneID
831743
NCBI Official Full Name
carboxyl-terminal domain (ctd) phosphatase-like 2
NCBI Official Symbol
CPL2
NCBI Official Synonym Symbols
ATCPL2; carboxyl-terminal domain (ctd) phosphatase-like 2; F7J8.250; F7J8_250
NCBI Protein Information
carboxyl-terminal domain (ctd) phosphatase-like 2
NCBI Summary
Encodes CPL2, a carboxyl-terminal domain (CTD) phosphatase that dephosphorylates CTD Ser5-PO4 of the RNA polymerase II complex. Regulates plant growth, stress and auxin responses.
UniProt Gene Name
CPL2
UniProt Synonym Gene Names
FCP-like 2; AtCPL2; CTD phosphatase-like 2
UniProt Protein Name
RNA polymerase II C-terminal domain phosphatase-like 2
UniProt Synonym Protein Names
Carboxyl-terminal phosphatase-like 2; AtCPL2; CTD phosphatase-like 2
UniProt Primary Accession #
Q5YDB5
UniProt Secondary Accession #
Q9LFA9; F4K803
UniProt Related Accession #
Q5YDB5
UniProt Comments
Processively dephosphorylates 'Ser-5' but not 'Ser-2' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II. Together with CPL1, required for male gametes fertility. Multifunctional regulator that modulates plant growth, stress, and phytohormones responses. Positive transcription regulator of genes involved in high salinity resistance and auxin mediated signaling pathway.

For research use only, not for clinical use.