Regulatory protein NPR6 (NPR6), Recombinant Protein
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Regulatory protein NPR6 (NPR6), Recombinant Protein

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Cat: RP02962
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Regulatory protein NPR6 (NPR6)
Product Gene Name
NPR6 recombinant protein
Product Synonym Gene Name
NPR6
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSNTFEESLK SMSLDYLNLL INGQAFSDVT FSVEGRLVHA HRCILAARSL FFRKFFCESD PSQPGAEPAN QTGSGARAAA VGGVIPVNSV GYEVFLLLLQ FLYSGQVSIV PHKHEPRSNC GDRGCWHTHC TAAVDLSLDI LAAARYFGVE QLALLTQKHL TSMVEKASIE DVMKVLIASR KQDMHQLWTT CSYLIAKSGL PQEILAKHLP IELVAKIEEL RLKSSMPLRS LMPHHHDLTS TLDLEDQKIR RMRRALDSSD VELVKLMVMG EGLNLDESLA LIYAVENCSR EVVKALLELG AADVNYPAGP TGKTALHIAA EMVSPDMVAV LLDHHADPNV QTVDGITPLD ILRTLTSDFL FKGAIPGLTH IEPNKLRLCL ELVQSAALVI SREEGNNNSN DNNTMIYPRM KDEHTSGSSL DSRLVYLNLG ATNRDIGDDN SNQREGMNLH HHHHDPSTMY HHHHHHF
Sequence Positions
1-467, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
51,785 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Regulatory protein

NCBI/Uniprot Data

NCBI Accession #
NP_191272.1
NCBI GI #
15230230
NCBI GenBank Nucleotide #
NM_115572.2
NCBI GeneID
824880
NCBI Official Full Name
Ankyrin repeat family protein / BTB/POZ domain-containing protein
NCBI Official Symbol
BOP1
NCBI Official Synonym Symbols
BLADE ON PETIOLE 1
NCBI Protein Information
Ankyrin repeat family protein / BTB/POZ domain-containing protein
NCBI Summary
Encodes BOP1. Contains Pfam domain, PF00023: Ankyrin repeat and Pfam domain, PF00651: BTB/POZ domain. Lines carrying recessive mutations exhibit a number of visible defects, most pronounced being ectopic outgrowths of in leaf petioles of rosette leaves. Along with BOP2, BOP1 is required for nectary development and formation of normal abscission zones.Forms homodimers and heterodimers with BOP2. Nuclear localization is required for activity which includes positive regulation of AS2 in leaves. BOP1/2 promotes floral meristem fate and determinacy in a pathway targetting APETALA1 and AGAMOUS-LIKE24. PUCHI, BOP1 and BOP2 are redundantly required for expression of LFY and AP1. BOP1 is expressed in valve margin. Misexpression in stems causes short internodes and ectopic biosynthesis of lignin. BOP1 activity is antagonistic to BP (At4g08150) and PNY (At5g02030). BOP1 expression is restricted to pedicel axils by BP and PNY. BOP1 promotes KNAT6 (At1g23380) expression.
UniProt Gene Name
NPR6
UniProt Synonym Gene Names
BOP1
UniProt Protein Name
Regulatory protein NPR6
UniProt Synonym Protein Names
BTB/POZ domain-containing protein NPR6; Protein BLADE-ON-PETIOLE 1
UniProt Primary Accession #
Q9M1I7
UniProt Related Accession #
Q9M1I7
UniProt Comments
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB, YAB1/FIL and YAB3, and through positive regulation of LOB domain-containing genes LOB, LBD6/AS2 and LBD36. Promotes and maintains a developmentally determinate state in leaf cells through the negative regulation of JAG, JGL and class I KNOX genes. Is also involved in nectary development, formation of normal abscission zones and suppression of bract formation.

For research use only, not for clinical use.