NCBI Accession #
NP_193699.1
NCBI GenBank Nucleotide #
NM_118084.5
NCBI Official Full Name
Ras-related small GTP-binding family protein
NCBI Official Symbol
ARA7
NCBI Official Synonym Symbols
ARA-7; ARABIDOPSIS RAB GTPASE HOMOLOG F2B; ATRAB-F2B; ATRAB5B; ATRABF2B; F24J7.190; F24J7_190; RAB GTPASE HOMOLOG F2B; RAB-F2B; RABF2B
NCBI Protein Information
Ras-related small GTP-binding family protein
NCBI Summary
Encodes Ara7.
UniProt Synonym Gene Names
AtRab5B
UniProt Protein Name
Ras-related protein RABF2b
UniProt Synonym Protein Names
Ras-related protein Ara-7
UniProt Primary Accession #
Q9SN68
UniProt Related Accession #
Q9SN68
UniProt Comments
Endosomal protein that may be involved in endocytosis (PubMed:16103374). Involved in the trafficking of proteins from prevacuolar compartments (PVCs) to vacuoles (PubMed:23682115, PubMed:24824487). May activate the MON1-CCZ1 complex which acts as guanine nucleotide exchange factors (GEF) for Rab7 protein family, and serves as a link between Rab5 and Rab7 families in PVCs, and mediates PVC maturation (PubMed:24824487). Involved in vacuolar transport of storage proteins with EREX as effector. Regulates membrane trafficking to protein storage vacuoles (PSVs) (PubMed:27288222).