NCBI Accession #
NP_568922.1
NCBI GenBank Nucleotide #
NM_125447.2
NCBI Official Full Name
pyridoxine biosynthesis 2
NCBI Official Symbol
PDX2
NCBI Official Synonym Symbols
ATPDX2; EMB2407; EMBRYO DEFECTIVE 2407; MUF9.1; MUF9_1; pyridoxine biosynthesis 2; PYRIDOXINE BIOSYNTHESIS 2
NCBI Protein Information
pyridoxine biosynthesis 2
NCBI Summary
Encodes a protein predicted to function in tandem with PDX1 to form glutamine amidotransferase complex with involved in vitamin B6 biosynthesis. PDX2 is predicted to function as glutaminase within the complex.
UniProt Synonym Gene Names
EMB2407; AtPDX2
UniProt Protein Name
Probable pyridoxal 5'-phosphate synthase subunit PDX2
UniProt Synonym Protein Names
Protein EMBRYO DEFECTIVE 2407; Pyridoxal 5'-phosphate synthase glutaminase subunit (EC:3.5.1.2
UniProt Primary Accession #
Q8LAD0
UniProt Secondary Accession #
Q56ZP9; Q9FKJ3
UniProt Related Accession #
Q8LAD0
UniProt Comments
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PDX1. Involved in the indirect resistance to singlet oxygen-generating photosensitizers.