Putative rRNA 2'-O-methyltransferase fibrillarin 3 (FIB3), Recombinant Protein
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Putative rRNA 2'-O-methyltransferase fibrillarin 3 (FIB3), Recombinant Protein

Cat: RP02258
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Putative rRNA 2'-O-methyltransferase fibrillarin 3 (FIB3)
Product Gene Name
FIB3 recombinant protein
Product Synonym Gene Name
FIB3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MKPPQRGRGG GVRGGRGLAR GGEGSAVRGS GRGGESGRGR GPGRVKSESD GGIKGGSKVL VTPHRHAGVF VAKSKADALV TKNLVPGEII YNEKRIFVQN EDRSTVEYRV WNPHRSKLAD AITTGVDNIW IKPGVKVLYL GASSGYTVSH VSDIVGPEGC VYAVEHSDIC GKVLMNMAEK RTNVIPIIED ARHPAKYRML VGMVDIIFSD VNHPEQANIL SLNASYFLKS GGHFMISIKA NSIDSTIAAE TVYQMEVEKL QMEELRPTEI LHLDSCEEKH ACVFGGYRLP RK
Sequence Positions
1-292, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
31,706 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Putative rRNA 2'-O-methyltransferase fibrillarin

NCBI/Uniprot Data

NCBI Accession #
NP_568773.1
NCBI GI #
18423398
NCBI GenBank Nucleotide #
NM_124628.1
NCBI GeneID
835325
NCBI Official Full Name
Fibrillarin family protein
NCBI Official Symbol
AT5G52490
NCBI Official Synonym Symbols
K24M7.24; K24M7_24
NCBI Protein Information
Fibrillarin family protein
UniProt Gene Name
FIB3
UniProt Protein Name
Putative rRNA 2'-O-methyltransferase fibrillarin 3
UniProt Synonym Protein Names
Fibrillarin-like protein 3; Histone-glutamine methyltransferase
UniProt Primary Accession #
Q9FHB3
UniProt Related Accession #
Q9FHB3
UniProt Comments
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus .

For research use only, not for clinical use.