NCBI Accession #
NP_196991.1
NCBI GenBank Nucleotide #
NM_121491.3
NCBI Official Full Name
cyclic nucleotide-gated channel 18
NCBI Official Symbol
CNGC18
NCBI Official Synonym Symbols
ATCNGC18; cyclic nucleotide-gated channel 18; CYCLIC NUCLEOTIDE-GATED CHANNEL 18; T9L3.170; T9L3_170
NCBI Protein Information
cyclic nucleotide-gated channel 18
NCBI Summary
Encodes a member of the cyclic nucleotide gated channel family that is asymmetrically localized to the plasma membrane at the growing tip of the pollen tube and is involved in pollen tube growth. It likely directly transduces a cNMP signal into an ion flux that can produce a localized signal capable of regulating the pollen tip-growth machinery.
UniProt Protein Name
Cyclic nucleotide-gated ion channel 18
UniProt Synonym Protein Names
Cyclic nucleotide- and calmodulin-regulated ion channel 18
UniProt Primary Accession #
Q9LEQ3
UniProt Related Accession #
Q9LEQ3
UniProt Comments
Cyclic nucleotide-gated ion channel required for directional pollen tube growth into the transmitting tract (PubMed:17726111, PubMed:26929345). Acts as a Ca2+-permeable divalent cation-selective channel inhibited by either lanthanum or gadolinium (PubMed:24380879). Regulated by CPK32 to mediate Ca2+ transport across the plasma membrane in response to Ca2+ oscillation (PubMed:24121288).