Putative bifunctional dihydrofolate reductase-thymidylate synthase (Os12g0446900, LOC_Os12g26060), Recombinant Protein
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Putative bifunctional dihydrofolate reductase-thymidylate synthase (Os12g0446900, LOC_Os12g26060), Recombinant Protein

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Cat: RP14535
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Oryza sativa subsp. japonica (Rice)
Datasheet:

Product Info

Full Product Name
Recombinant Oryza sativa subsp. japonica Putative bifunctional dihydrofolate reductase-thymidylate synthase (Os12g0446900, LOC_Os12g26060)
Product Gene Name
Os12g0446900 recombinant protein
Product Synonym Gene Name
Os12g0446900; LOC_Os12g26060
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MGIGKDGTLP WKLPGDLKFF KDITVTTSDP SKKNAVVMGR KTWESIPLKF RPLPGRLNVI LTRSGSFDFA TAENVVICGS LDSALQLLAT TPYCLTVEKT FIIGGGEILR QSLNAPACEA IHLTDIESSI ECDTFIPPID LSMFHPWYSS FPVVENGIKH SFISFVRVTK SIAEANDSSG KELTGNDSKK VKFEIENFSF LPKMIFERHE EYQYLNLVQD IIRNGAKKND RTGTGTVSKF GCQMRFNLRR NFPLLTTKRV FWRGVLEELL WFISGSTNAK VLQEKGIHIW DGNASRQYLD SIGLTQREEG DLGPVYGFQW RHFGAEYTDM HADYVGKGFD QLMDVIDKIK NNPDDRRIIL SAWNPTDLKK MALPPCHMFA QFYVENGELS CQMYQRSADM GLGVPFNIAS YSLLTCMIAQ VCDLSPGDFV HVIGDAHVYR THVEALEEQM RKQPKPFPIL KINPVKKDID SFVTSDFKLV RYDPHHKIEM KMAV
Sequence Positions
1-494, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
55,977 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Putative bifunctional dihydrofolate reductase-thymidylate synthase

NCBI/Uniprot Data

NCBI Accession #
Q2QRX6.2
NCBI GI #
110808211
NCBI Official Full Name
Putative bifunctional dihydrofolate reductase-thymidylate synthase
UniProt Gene Name
Os12g0446900
UniProt Synonym Gene Names
DHFR-TS
UniProt Protein Name
Putative bifunctional dihydrofolate reductase-thymidylate synthase
UniProt Primary Accession #
Q2QRX6
UniProt Comments
Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP .

For research use only, not for clinical use.