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Putative auxin efflux carrier component 8 (PIN8), Recombinant Protein
Cat: RP03228
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Putative auxin efflux carrier component 8 (PIN8), partial
Product Gene Name
PIN8 recombinant protein
Product Synonym Gene Name
PIN8
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
38,573 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Probable auxin efflux carrier component
NCBI/Uniprot Data
NCBI Accession #
NP_197157.4
NCBI GI #
240256298
NCBI GenBank Nucleotide #
NM_121659.5
NCBI GeneID
831515
NCBI Official Full Name
Auxin efflux carrier family protein
NCBI Official Symbol
PIN5
NCBI Official Synonym Symbols
MQK4.28; MQK4_28; PIN-FORMED 5
NCBI Protein Information
Auxin efflux carrier family protein
NCBI Summary
Encodes PIN5, an atypical member of the PIN family. PIN5 is a functional auxin transporter that is required for auxin-mediated development. PIN5 does not have a direct role in cell-to-cell transport but regulates intracellular auxin homeostasis and metabolism. PIN5 localizes, unlike other characterized plasma membrane PIN proteins, to endoplasmic reticulum (ER), presumably mediating auxin flow from the cytosol to the lumen of the ER. It acts together with PIN8 in affecting pollen development and auxin homeostasis.
UniProt Gene Name
PIN5
UniProt Synonym Gene Names
AtPIN5
UniProt Protein Name
Auxin efflux carrier component 5
UniProt Primary Accession #
Q9FFD0
UniProt Related Accession #
Q9FFD0
UniProt Comments
Auxin transporter regulating intracellular auxin homeostasis and metabolism (PubMed:19506555, PubMed:20439545). Mediates the auxin transport from the cytosol into the lumen of the endoplasmic reticulum (PubMed:19506555). May also act as an auxin efflux carrier when located to the cell membrane (PubMed:24692422). PIN5 and PIN8 may have an antagonistic/compensatory activity (PubMed:22760640, PubMed:22990451). Involved in unfolded protein response (UPR) activation (PubMed:24180465). Involved in the control of vein patterning (PubMed:24304505). Promotes vein formation (PubMed:26560462). PIN5, PIN6, and PIN8 control vein network geometry, but they are expressed in mutually exclusive domains of leaf vascular cells (PubMed:26560462).
For research use only, not for clinical use.