NCBI Accession #
NP_197014.1
NCBI GenBank Nucleotide #
NM_121514.2
NCBI Official Full Name
Auxin efflux carrier family protein
NCBI Official Symbol
PIN8
NCBI Official Synonym Symbols
ATPIN8; F2G14.220; F2G14_220; PIN-FORMED 8
NCBI Protein Information
Auxin efflux carrier family protein
NCBI Summary
Encodes an auxin transporter with a strong expression in a male gametophyte. Mutant studies reveal a role for auxin transport in regulating pollen development and function. It acts together with PIN5.
UniProt Synonym Gene Names
AtPIN8
UniProt Protein Name
Auxin efflux carrier component 8
UniProt Primary Accession #
Q9LFP6
UniProt Related Accession #
Q9LFP6
UniProt Comments
Component of the intracellular auxin-transport pathway in the male gametophyte (PubMed:20439545, PubMed:22540348). Involved in the regulation of auxin homeostasis in pollen (PubMed:22540348). Involved in the efflux of auxin from the endoplasmic reticulum into the cytoplasm (PubMed:22760640). PIN5 and PIN8 may have an antagonistic/compensatory activity (PubMed:22760640, PubMed:22990451). Involved in the control of vein patterning (PubMed:23437008, PubMed:24304505). Redundantly with PIN6, inhibits the vein-formation-promoting functions of PIN5 (PubMed:26560462). PIN5, PIN6, and PIN8 control vein network geometry, but they are expressed in mutually exclusive domains of leaf vascular cells (PubMed:26560462).