NCBI Accession #
NP_001320287.1
NCBI GenBank Nucleotide #
NM_001331750.1
NCBI Official Full Name
tyrosylprotein sulfotransferase
NCBI Official Symbol
TPST
NCBI Official Synonym Symbols
active quiescent center1; AQC1; HPS7; hypersensitive to Pi starvation 7; T6D22.29; T6D22_29; tyrosylprotein sulfotransferase
NCBI Protein Information
tyrosylprotein sulfotransferase
NCBI Summary
Encodes a tyrosylprotein sulfotransferase (TPST). This protein is a 500-aa type I transmembrane protein that shows no sequence similarity to animal TPSTs. Activity confirmed by protein expression in yeast. TPST is expressed throughout the plant body, and the highest levels of expression are in the root apical meristem. TPST acts in the auxin pathway to maintain postembryonic root stem cell niche by defining the expression of the PLETHORA stem cell transcription factor genes. A loss-of-function mutant TPST displayed a marked dwarf phenotype accompanied by stunted roots, pale green leaves, reduction in higher order veins, early senescence, and a reduced number of flowers and siliques.
UniProt Protein Name
Protein-tyrosine sulfotransferase
UniProt Synonym Protein Names
Tyrosylprotein sulfotransferase
UniProt Primary Accession #
Q3EDG5
UniProt Secondary Accession #
Q9LN06; C7G3K4
UniProt Related Accession #
Q3EDG5
UniProt Comments
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides.