NCBI Accession #
NP_001319041.1
NCBI GenBank Nucleotide #
NM_001332386.1
NCBI Official Full Name
jasmonate-zim-domain protein 1
NCBI Official Symbol
JAZ1
NCBI Official Synonym Symbols
AtJAZ1; jasmonate-zim-domain protein 1; T29M8.5; T29M8_5; TIFY10A
NCBI Protein Information
jasmonate-zim-domain protein 1
NCBI Summary
JAZ1 is a nuclear-localized protein involved in jasmonate signaling. JAZ1 transcript levels rise in response to a jasmonate stimulus. JAZ1 can interact with the COI1 F-box subunit of an SCF E3 ubiquitin ligase in a yeast-two-hybrid assay only in the presence of jasmonate-isoleucine (JA-ILE) or coronatine. Application of jasmonate methyl ester to Arabidopsis roots reduces the levels of a JAZ1:GUS fusion protein, presumably by stimulating ubiquitin-proteasome-mediated degradation. The Jas domain appears to be important for JAZ1-COI1 interactions in the presence of coronatine. Two positive residues (R205 and R206) in the Jas domain shown to be important for coronatine -dependent COI1 binding are not required for binding AtMYC2.
UniProt Gene Name
TIFY10A
UniProt Synonym Gene Names
JAZ1
UniProt Protein Name
Protein TIFY 10A
UniProt Synonym Protein Names
Jasmonate ZIM domain-containing protein 1
UniProt Primary Accession #
Q9LMA8
UniProt Secondary Accession #
Q8LAG5; Q93Z09
UniProt Related Accession #
Q9LMA8
UniProt Comments
Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10A/JAZ1 interaction. Interacts with COI1 and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor.