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Protein SGT1 homolog B (SGT1B), Recombinant Protein
Cat: RP04481
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein SGT1 homolog B (SGT1B)
Product Gene Name
SGT1B recombinant protein
Product Synonym Gene Name
SGT1B
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAKELAEKAK EAFLDDDFDV AVDLYSKAID LDPNCAAFFA DRAQANIKID NFTEAVVDAN KAIELEPTLA KAYLRKGTAC MKLEEYSTAK AALEKGASVA PNEPKFKKMI DECDLRIAEE EKDLVQPMPP SLPSSSTTPL ATEADAPPVP IPAAPAKPMF RHEFYQKPEE AVVTIFAKKV PKENVTVEFG EQILSVVIDV AGEEAYHLQP RLFGKIIPEK CRFEVLSTKV EIRLAKAEII TWASLEYGKG QSVLPKPNVS SALSQRPVYP SSKPAKDWDK LEAEVKKQEK DEKLDGDAAM NKFFSDIYSS ADEDMRRAMN KSFAESNGTV LSTNWKEVGT KKVESTPPDG MELKKWEY
Sequence Positions
1-358, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
39,762 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein
NCBI/Uniprot Data
NCBI Accession #
NP_192865.1
NCBI GI #
15237122
NCBI GenBank Nucleotide #
NM_117197.4
NCBI GeneID
826728
NCBI Official Full Name
phosphatase-like protein
NCBI Official Symbol
SGT1B
NCBI Official Synonym Symbols
ATSGT1B; EDM1; ENHANCED DOWNY MILDEW 1; ENHANCER OF TIR1-1 AUXIN RESISTANCE 3; ETA3; F8L21.50; F8L21_50; RPR1
NCBI Protein Information
phosphatase-like protein
NCBI Summary
Functions in plant disease resistance signaling, SCF(TIR1) mediated degradation of Aux/IAA proteins and HSP90 mediated degradation of R resistance proteins. AtSGT1a and AtSGT1b are functionally redundant in the resistance to pathogenes. AtSGT1b was more highly expressed than AtSGT1. The N-terminal TPR domain of AtSGT1a reduces the steady-state level of Arabidopsis SGT1 proteins whereas the same domain from AtSGT1b enhances SGT1 accumulation. The TPR domain is dispensable for SGT1 resistance.
UniProt Gene Name
SGT1B
UniProt Synonym Gene Names
EDM1; ETA3; RPR1; AtSGT1b
UniProt Protein Name
Protein SGT1 homolog B
UniProt Synonym Protein Names
Protein ENHANCED DOWNY MILDEW 1; Protein ENHANCER OF TIR1-1 AUXIN RESISTANCE 3; Suppressor of G2 allele of SKP1 homolog B
UniProt Primary Accession #
Q9SUT5
UniProt Related Accession #
Q9SUT5
UniProt Comments
Involved in plant innate immunity. Is essential for resistance conferred by multiple R genes recognizing different oomycete pathogen isolates like avirulent H.parasitica (downy mildew). Contributes additively with RAR1 to RPP5-dependent resistance. Not required for RPM1, RPS2, RPS4 and RPS5-mediated resistance. Functions as negative regulator of RPS5 accumulation by assisting its degradation. May be involved in heat shock response by associating with HSC70-1 chaperone. Required for the SCF(TIR1)-mediated degradation of Aux/IAA proteins, but maybe not for SCF(TIR1) assembly or binding to its Aux/IAA substrates. Probably required for SCF-mediated ubiquitination, by coupling HSP90 to SCF complex for ubiquitination of HSP90 client proteins. Required for the coronatine/jasmonic acid-mediated signal transduction pathway.
For research use only, not for clinical use.