NCBI Accession #
NP_001031704.1
NCBI GenBank Nucleotide #
NM_001036627.2
NCBI Official Full Name
phosphatase-like protein
NCBI Official Symbol
SGT1A
NCBI Official Synonym Symbols
F9D16.40; F9D16_40
NCBI Protein Information
phosphatase-like protein
NCBI Summary
Closely related to SGT1B, may function in SCF(TIR1) mediated protein degradation. AtSGT1a and AtSGT1b are functionally redundant in the resistance to pathogenes. AtSGT1b was more highly expressed than AtSGT1. The N-terminal TPR domain of AtSGT1a reduces the steady-state level of Arabidopsis SGT1 proteins whereas the same domain from AtSGT1b enhances SGT1 accumulation. The TPR domain is dispensable for SGT1 resistance. AtSGT1a is induced upon pathogen infection and can function in R gene-mediated resistance.
UniProt Synonym Gene Names
AtSGT1a
UniProt Protein Name
Protein SGT1 homolog A
UniProt Synonym Protein Names
Suppressor of G2 allele of SKP1 homolog A
UniProt Primary Accession #
Q9SUR9
UniProt Secondary Accession #
Q84LL4; Q8W515
UniProt Related Accession #
Q9SUR9
UniProt Comments
Functions in R gene-mediated resistance, but participates in a lower extent than SGT1B to RPP5-mediated resistance. Not required for RPM1, RPS2, RPS4 and RPS5-mediated resistance. Probably required for SCF-mediated ubiquitination, by coupling HSP90 to SCF complex for ubiquitination of HSP90 client proteins.