NCBI Accession #
NP_568068.1
NCBI GenBank Nucleotide #
NM_120135.5
NCBI Official Full Name
Thioredoxin superfamily protein
NCBI Official Symbol
HCC2
NCBI Official Synonym Symbols
homologue of copper chaperone SCO1 2; T19P19.130; T19P19_130
NCBI Protein Information
Thioredoxin superfamily protein
NCBI Summary
Encodes HCC2, one of the two Arabidopsis genes (HCC1 and HCC2) resulting from a duplication with homology to the SCO proteins involved in copper insertion during cytochrome c oxidase (COX) assembly in other organisms. HCC2, which lacks the cysteines and histidine putatively involved in copper binding, functions in copper sensing and redox homeostasis.
UniProt Synonym Gene Names
SCO1-2; HCC2
UniProt Protein Name
Protein SCO1 homolog 2, mitochondrial
UniProt Synonym Protein Names
Homolog of the copper chaperone SCO1 member 2; HCC2
UniProt Primary Accession #
Q8LAL0
UniProt Secondary Accession #
O65661
UniProt Related Accession #
Q8LAL0
UniProt Comments
Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX . Participates in copper and redox homeostasis.