NCBI Accession #
NP_566339.1
NCBI GenBank Nucleotide #
NM_111729.3
NCBI Official Full Name
electron transport SCO1/SenC family protein
NCBI Official Symbol
HCC1
NCBI Official Synonym Symbols
homologue of the copper chaperone SCO1
NCBI Protein Information
electron transport SCO1/SenC family protein
NCBI Summary
Encodes HCC1, homologue of the copper chaperone SCO1 (synthesis of cytochrome c oxidase 1) from the yeast Saccharomyces cerevisiae. SCO1 encodes a mitochondrial protein that is essential for the correct assembly of complex IV in the respiratory chain. HCC1 is localized in the mitochondrion. A chimeric yeast Sco1-Arabidopsis HCC1 protein complements yeast Sco1 activity. Embryos of hcc1 mutants became arrested at various developmental stages, mostly at the heart stage.
UniProt Synonym Gene Names
SCO1-1; HCC1
UniProt Protein Name
Protein SCO1 homolog 1, mitochondrial
UniProt Synonym Protein Names
Homolog of the copper chaperone SCO1 member 1; HCC1
UniProt Primary Accession #
Q8VYP0
UniProt Secondary Accession #
Q9SR94
UniProt Related Accession #
Q8VYP0
UniProt Comments
Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX. Plays an essential role in embryo development.