Protein SCAR2 (SCAR2), Recombinant Protein
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Protein SCAR2 (SCAR2), Recombinant Protein

Cat: RP05485
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Protein SCAR2 (SCAR2) , partial
Product Gene Name
SCAR2 recombinant protein
Product Synonym Gene Name
SCAR2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
151,585 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein

NCBI/Uniprot Data

NCBI Accession #
NP_181378.2
NCBI GI #
30687512
NCBI GenBank Nucleotide #
NM_129400.3
NCBI GeneID
818425
NCBI Official Full Name
SCAR homolog 2
NCBI Official Symbol
SCAR2
NCBI Official Synonym Symbols
ATSCAR2; DIS3; IRREGULAR TRICHOME BRANCH1; IRREGULAR TRICHOME BRANCH1; ITB1; SCAR homolog 2; SCAR HOMOLOG 2; T19C21.7; T19C21_7; WAVE4
NCBI Protein Information
SCAR homolog 2
NCBI Summary
Encodes a subunit of the WAVE complex. The WAVE complex is required for activation of ARP2/3 complex which functions in actin microfilament nucleation and branching. Mutations cause defects in both the actin and microtubule cytoskeletons that result in aberrant epidermal cell expansion. itb1 mutants showed irregularities in trichome branch positioning and expansion. The SHD domain of this protein binds to BRK1 and overexpression of the SHD domain results in a dominant negative phenotype.
UniProt Gene Name
SCAR2
UniProt Synonym Gene Names
DIS3; ITB1; WAVE4; AtSCAR2
UniProt Protein Name
Protein SCAR2
UniProt Synonym Protein Names
Protein DISTORTED 3; Protein IRREGULAR TRICHOME BRANCH 1; Protein WAVE4
UniProt Primary Accession #
Q5XPJ9
UniProt Secondary Accession #
O80907
UniProt Related Accession #
Q5XPJ9
UniProt Comments
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. Regulates trichome branch positioning and expansion.

For research use only, not for clinical use.