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Protein-S-isoprenylcysteine O-methyltransferase A (ICMTA), Recombinant Protein
Cat: RP05949
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein-S-isoprenylcysteine O-methyltransferase A (ICMTA), partial
Product Gene Name
ICMTA recombinant protein
Product Synonym Gene Name
ICMTA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
22,525 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein-S-isoprenylcysteine O-methyltransferase
NCBI/Uniprot Data
NCBI Accession #
NP_197723.1
NCBI GI #
15237283
NCBI GenBank Nucleotide #
NM_122238.2
NCBI GeneID
832396
NCBI Official Full Name
S-isoprenylcysteine O-methyltransferase
NCBI Official Symbol
STE14A
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA ISOPRENYL CYSTEINE METHYLTRANSFERASE A; ATICMTA; ATPCM; ATSTE14; ATSTE14A; homolog of yeast STE14 A; ICMTA; ISOPRENYL CYSTEINE METHYLTRANSFERASE A; LPHA-CARBOXYL METHYLTRANSFERASE; MKD15.18; MKD15_18; PRENYLCYSTEINE ALPHA-CARBOXYL MET
NCBI Protein Information
S-isoprenylcysteine O-methyltransferase
NCBI Summary
Encodes a prenylcysteine alpha-carboxyl methyltransferase involved in methylation of isoprenylated proteins. This protein appears to have lower catalytic activity and a lower transcript expression level than the other ICMT present in Arabidopsis (At5g08335). Analysis of ICMT RNAi lines suggests that this protein may be involved in flower and stem development.
UniProt Gene Name
ICMTA
UniProt Synonym Gene Names
PCM; STE14; STE14A; AtICMTA; AtPCM
UniProt Protein Name
Protein-S-isoprenylcysteine O-methyltransferase A
UniProt Synonym Protein Names
Isoprenylcysteine carboxylmethyltransferase A; Prenylated protein carboxyl methyltransferase A; Prenylcysteine carboxyl methyltransferase A; AtPCM
UniProt Primary Accession #
Q9FMW9
UniProt Secondary Accession #
A0MFH5
UniProt Related Accession #
Q9FMW9
UniProt Comments
Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues, resulting in the modulation of the function of prenylated proteins. Involved in negative regulation of abscisic acid signaling. Carboxyl methylation is a reversible and potentially regulated step in the post-translational modification of prenylated proteins.
For research use only, not for clinical use.