Protein FRIGIDA (FRI), Recombinant Protein

Full Product Name

Recombinant Arabidopsis thaliana Protein FRIGIDA (FRI) , partial

Product Gene Name

FRI recombinant protein

Purity

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Molecular Weight

68,443 Da

Storage

Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

Protein Family

Protein

NCBI Accession #

P0DH90.1

NCBI GI #

374110564

NCBI Official Full Name

Protein FRIGIDA

UniProt Gene Name

FRI

UniProt Protein Name

Protein FRIGIDA

UniProt Primary Accession #

P0DH90

UniProt Secondary Accession #

O65274; Q9FDW0

UniProt Comments

Required for the regulation of flowering time in the late-flowering phenotype. Involved in the enrichment of a WDR5A-containing COMPASS-like complex at the 'FLOWERING LOCUS C' that trimethylates histone H3 'Lys-4', leading to FLC up-regulation and RNA levels increase (PubMed:19567704). Variants with an early-flowering phenotype (Including cv. Columbia, cv. Landsberg Erecta and cv. Wassilewskija) show loss-of-function mutations of FRI. Able to delay flowering independently of FRL1 activity. Dispensable for the reactivation of FLC in early embryogenesis, but required to maintain high levels of FLC expression in later embryonic and vegetative development. Suppresses the repression of FLC by the autonomous pathway, but has no effect on the expression of the genes involved in this pathway.