NCBI Accession #
NP_564442.1
NCBI GenBank Nucleotide #
NM_103147.3
NCBI Official Full Name
Putative membrane lipoprotein
NCBI Official Symbol
EPF2
NCBI Official Synonym Symbols
EPIDERMAL PATTERNING FACTOR 2
NCBI Protein Information
Putative membrane lipoprotein
NCBI Summary
Encodes a secretory peptide EPF2 expressed in proliferating cells of the stomatal lineage, known as meristemoids, and in guard mother cells, the progenitors of stomata. Controls asymmetric cell divisions during stomatal development. EPF2 is related to EPF1, also involved in stomatal development. Its transcript levels change after inducing MUTE expression in a mute background.
UniProt Protein Name
Protein EPIDERMAL PATTERNING FACTOR 2
UniProt Primary Accession #
Q8LC53
UniProt Related Accession #
Q8LC53
UniProt Comments
Controls stomatal patterning. Regulates the number of cells that enter, and remain in, the stomatal lineage by inhibiting protodermal cells from adopting the meristemoid mother cell (MMC) fate in a non-cell-autonomous manner. Mediates stomatal development inhibition. MEPF2: mobile signal controlling stomatal development in a non-cell-autonomous manner (PubMed:22241782). Uses ERECTA as major receptor (PubMed:22241782). Inactivated by cleavage by CRSP (AC Q9LNU1) (PubMed:25043023). May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1) (PubMed:22027592).