NCBI Accession #
NP_001332209.1
NCBI GenBank Nucleotide #
NM_001344934.1
NCBI Official Full Name
SWITCH1
NCBI Official Symbol
SWI1
NCBI Official Synonym Symbols
DYAD; MFG13.3; MFG13_3; SWITCH1
NCBI Protein Information
SWITCH1
NCBI Summary
Encodes novel protein involved in sister chromatid cohesion and meiotic chromosome organization during both male and female meiosis. Gene has two alternate transcripts which produce two similar proteins, one 57 aa shorter than the other.
UniProt Synonym Gene Names
SWI1
UniProt Protein Name
Protein DYAD
UniProt Synonym Protein Names
Protein SWITCH 1
UniProt Primary Accession #
Q9FGN8
UniProt Secondary Accession #
Q946Y3
UniProt Related Accession #
Q9FGN8
UniProt Comments
Required for fertility. Involved in chromatid cohesion establishment, in chromosome structure during male and female meiosis (e.g. the synapse formation between homologous chromosomes, the recombination, and the cohesion of both chromatid arm and centromere), and in axial element formation. Regulates the switch from mitosis to the reductional meiosis division of megaspores prior to the female gametogenesis (megasporogenesis).