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Protein BREAST CANCER SUSCEPTIBILITY 1 homolog (BRCA1), Recombinant Protein
Cat: RP04800
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein BREAST CANCER SUSCEPTIBILITY 1 homolog (BRCA1) , partial
Product Gene Name
BRCA1 recombinant protein
Product Synonym Gene Name
BRCA1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
103,922 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein BREAST CANCER SUSCEPTIBILITY
NCBI/Uniprot Data
NCBI Accession #
NP_193839.4
NCBI GI #
79480107
NCBI GenBank Nucleotide #
NM_118225.5
NCBI GeneID
827854
NCBI Official Full Name
breast cancer susceptibility1
NCBI Official Symbol
BRCA1
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA BREAST CANCER SUSCEPTIBILITY1; ATBRCA1; breast cancer susceptibility1
NCBI Protein Information
breast cancer susceptibility1
NCBI Summary
Encodes AtBRCA1, an ortholog of the human breast cancer susceptibility gene 1. Contains one N-terminal RING finger, two C-terminal BRCT and the p300/CBP interacting domain. Strongly induced by gamma rays, consistent with a putative role in DNA repair and in cell cycle control.
UniProt Gene Name
BRCA1
UniProt Synonym Gene Names
AtBRCA1
UniProt Protein Name
Protein BREAST CANCER SUSCEPTIBILITY 1 homolog
UniProt Primary Accession #
Q8RXD4
UniProt Secondary Accession #
Q9SUA7
UniProt Related Accession #
Q8RXD4
UniProt Comments
Plays a role in DNA repair and in cell-cycle control. Required for the repair of DNA double-strand breaks (DSBs), both natural and induced by genotoxic stress, by homologous recombination (HR).
For research use only, not for clinical use.