Protein BRASSINAZOLE-RESISTANT 2 (BZR2), Recombinant Protein
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Protein BRASSINAZOLE-RESISTANT 2 (BZR2), Recombinant Protein

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Cat: RP02442
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Protein BRASSINAZOLE-RESISTANT 2 (BZR2)
Product Gene Name
BZR2 recombinant protein
Product Synonym Gene Name
BZR2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MTSDGATSTS AAAAAAAMAT RRKPSWRERE NNRRRERRRR AVAAKIYTGL RAQGNYNLPK HCDNNEVLKA LCSEAGWVVE EDGTTYRKGH KPLPGDMAGS SSRATPYSSH NQSPLSSTFD SPILSYQVSP SSSSFPSPSR VGDPHNISTI FPFLRNGGIP SSLPPLRISN SAPVTPPVSS PTSRNPKPLP TWESFTKQSM SMAAKQSMTS LNYPFYAVSA PASPTHHRQF HAPATIPECD ESDSSTVDSG HWISFQKFAQ QQPFSASMVP TSPTFNLVKP APQQLSPNTA AIQEIGQSSE FKFENSQVKP WEGERIHDVA MEDLELTLGN GKAHS
Sequence Positions
1-335, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
36,486 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein

NCBI/Uniprot Data

NCBI Accession #
NP_001077562.1
NCBI GI #
145323946
NCBI GenBank Nucleotide #
NM_001084093.1
NCBI GeneID
838518
NCBI Official Full Name
Brassinosteroid signaling positive regulator (BZR1) family protein
NCBI Official Symbol
BES1
NCBI Official Synonym Symbols
107 PROTEIN; BRASSINAZOLE-RESISTANT 2; BRI1-EMS-SUPPRESSOR 1; BZR2; F18O14.7; F18O14_7
NCBI Protein Information
Brassinosteroid signaling positive regulator (BZR1) family protein
NCBI Summary
Encodes brassinosteroid (BR) signalling protein that accumulates in the nucleus as dephosphorylated form in response to BRs. Is phosphorylated by the BIN2 GSK3 kinase. It synergistically interacts with BIM1 to bind to E box sequences (CANNTG). The protein contains a nuclear localization signal (NLS), followed by a highly conserved amino-terminal domain (N) shared by all family members, a BIN2 phosphorylation domain (P), a PEST motif, involved in protein degradation in the absence of BR, and a carboxyl-terminal domain. BES1 can interact with the ELF6 and REF6 Jumonji N/C-domain containing proteins and may direct them to modify histone methylation upstream of some brassinosteroid responsive-genes. Works with BRAVO to regulate QC division in the root.
UniProt Gene Name
BZR2
UniProt Protein Name
Protein BRASSINAZOLE-RESISTANT 2
UniProt Synonym Protein Names
Protein 107; Protein BIN2 SUBSTRATE 1
UniProt Primary Accession #
Q9LN63
UniProt Secondary Accession #
Q8LCX8; Q94JU1; Q9SEG5
UniProt Related Accession #
Q9LN63
UniProt Comments
Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610).

For research use only, not for clinical use.