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Protein argonaute 7 (AGO7), Recombinant Protein
Cat: RP02588
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein argonaute 7 (AGO7) , partial
Product Gene Name
AGO7 recombinant protein
Product Synonym Gene Name
AGO7
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
113,397 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein argonaute
NCBI/Uniprot Data
NCBI Accession #
NP_177103.1
NCBI GI #
15222321
NCBI GenBank Nucleotide #
NM_105611.5
NCBI GeneID
843276
NCBI Official Full Name
Argonaute family protein
NCBI Official Symbol
AGO7
NCBI Official Synonym Symbols
ARGONAUTE7; F10D13.11; F10D13_11; ZIP; ZIPPY
NCBI Protein Information
Argonaute family protein
NCBI Summary
Encodes ARGONAUTE7, a member of the ARGONAUTE family, characterised by the presence of PAZ and PIWI domains. Involved in the regulation of developmental timing. Required for the accumulation of TAS3 ta-siRNAs but not for accumulation of miR171, miR173, miR390 or mi391. Localized in mature rosette leaves and floral buds.
UniProt Gene Name
AGO7
UniProt Synonym Gene Names
ZIP
UniProt Protein Name
Protein argonaute 7
UniProt Synonym Protein Names
Protein ZIPPY
UniProt Primary Accession #
Q9C793
UniProt Related Accession #
Q9C793
UniProt Comments
Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Required for the processing of 21 nucleotide trans-acting siRNAs (ta-siRNAs) derived from TAS3a transcripts. Associates preferentially with the microRNA (miRNA) miR390 which guides the cleavage of TAS3 precursor RNA. Seems to act as miR390 specific slicer. Associates mainly with small RNAs of 21 nucleotide in length and with a 5' terminal adenosine. Acts in the RDR6/SGS3/DCL4/AGO7 trans-acting siRNA pathway involved in leaf developmental timing. Does not seems to act on leaf polarity. Required for the production of the 30-40nt bacterial-induced long siRNAs (lsiRNA). Involved in antiviral RNA silencing by contributing to efficient viral RNAs clearance. Targets less structured viral RNAs than AGO1 which is capable of targeting RNAs with more compact structures.
For research use only, not for clinical use.