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Protein argonaute 5 (AGO5), Recombinant Protein
Cat: RP02351
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Protein argonaute 5 (AGO5) , partial
Product Gene Name
AGO5 recombinant protein
Product Synonym Gene Name
AGO5
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
111,089 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protein argonaute
NCBI/Uniprot Data
NCBI Accession #
NP_850110.1
NCBI GI #
30683679
NCBI GenBank Nucleotide #
NM_179779.3
NCBI GeneID
817334
NCBI Official Full Name
Argonaute family protein
NCBI Official Symbol
AGO5
NCBI Official Synonym Symbols
ARGONAUTE 5; AtAGO5; T1E2.20; T1E2_20
NCBI Protein Information
Argonaute family protein
UniProt Gene Name
AGO5
UniProt Protein Name
Protein argonaute 5
UniProt Primary Accession #
Q9SJK3
UniProt Related Accession #
Q9SJK3
UniProt Comments
Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates with siRNAs of various sizes, from 21-24 nucleotide in length and preferentially recruits small RNAs with a 5' terminal cytosine. Probably involved in antiviral RNA silencing. Associates with siRNAs derived from cucumber mosaic virus (CMV). Targeted by the turnip yellows virus (TuYV) protein P0 (via F-box-like domain) for probable proteasome degradation and thereby inactivating AGO5 function in RNA silencing.
For research use only, not for clinical use.