Protection of telomeres protein 1a (POT1A), Recombinant Protein
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Protection of telomeres protein 1a (POT1A), Recombinant Protein

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Cat: RP05198
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Protection of telomeres protein 1a (POT1A)
Product Gene Name
POT1A recombinant protein
Product Synonym Gene Name
POT1A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAKKRESPKL IKIKDAIKLI NQQVSLIGIV LEQREPKQCR NNDWICTLRI IDDTYPSPGL TVNVFSKTLE QLPQIKNHDD MILFTRIKMQ TFDSGERVNA ACSRWVSSFA LFEGVDFVCY QCSTNFHEEE ALYKSAMDDL RKVFAGCSQV IKAMQSISYR TKPCSEVFSF LREIKIGKRF DLVCRILHAD EDTSAVFVWD GTDAPPASIL AKRSEEDKAF SSLSVHTLLS RDVLLSFPTV GTILRVHLSS HLFYRVKPGD WVKLYHLLCE VDRGSWVIKV TSSTKVHHLA QDDRLVEKIM RIYDKRLSSK LGHISFWCFP SPPGLTETDD NCAPFVTLMD IITFPKVTCK YRCIVRVVAA YPWQVEDFCS DENRRHHQVL LTLEDSTATL EAFLCNKDAE YFWGLGFQDT ETLRKKRNWL LGIRESSNFV APRNPPWIEC CILSYYTNKA DPWNTRLYRI FGTRLLH
Sequence Positions
1-467, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
22,895 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Protection of telomeres protein

NCBI/Uniprot Data

NCBI Accession #
NP_001118270.1
NCBI GI #
186499448
NCBI GenBank Nucleotide #
NM_001124798.2
NCBI GeneID
815069
NCBI Official Full Name
Nucleic acid-binding, OB-fold-like protein
NCBI Official Symbol
AtPOT1a
NCBI Official Synonym Symbols
ATPOT1; F5G3.11; F5G3_11; Protection of Telomeres 1a
NCBI Protein Information
Nucleic acid-binding, OB-fold-like protein
NCBI Summary
Encodes AtPOT1a, an accessory factor for telomerase required for positive telomere length regulation. Note on nomenclature: different names have been given to Arabidopsis POT-like genes (Kuchar and Fajkus, 2004; Shakirov et al, 2005; Tani and Murata, 2005). According to a unifying nomenclature (Surovtseva et al, 2007), At2g05210 (previously named AtPOT1) is designated AtPOT1a, while At5g06310 (previously named AtPOT2) is designated AtPOT1b.
UniProt Gene Name
POT1A
UniProt Synonym Gene Names
POT1; AtPOT1a
UniProt Protein Name
Protection of telomeres protein 1a
UniProt Synonym Protein Names
Protection of telomeres protein 1
UniProt Primary Accession #
Q56Y52
UniProt Secondary Accession #
Q4W6W9; Q4W6X0; Q52VR7; Q6Q835; Q9SJ37
UniProt Related Accession #
Q56Y52
UniProt Comments
Component of the telomerase ribonucleoprotein (RNP) complex that is essential for positive telomere length regulation. Binds specifically the telomerase RNA template component TER1. Does not bind single-stranded telomeric DNA. Not required to recruit telomerase to telomeres, but stimulates TER1 RNP repeat addition processivity (PubMed:25329641).

For research use only, not for clinical use.