NCBI Accession #
NP_188046.1
NCBI GenBank Nucleotide #
NM_112287.4
NCBI Official Full Name
20S proteasome alpha subunit E2
NCBI Official Symbol
PAE2
NCBI Official Synonym Symbols
20S proteasome alpha subunit E2; 20S PROTEASOME SUBUNIT PAE2
NCBI Protein Information
20S proteasome alpha subunit E2
NCBI Summary
Encodes 20S proteasome subunit PAE2 (PAE2) that has RNase activity.
UniProt Synonym Gene Names
PRCZ
UniProt Protein Name
Proteasome subunit alpha type-5-B
UniProt Synonym Protein Names
20S proteasome alpha subunit E-2; Proteasome component Z
UniProt Primary Accession #
Q42134
UniProt Related Accession #
Q42134
UniProt Comments
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.