NCBI Accession #
NP_199093.1
NCBI GenBank Nucleotide #
NM_123644.5
NCBI Official Full Name
proteasome alpha subunit F1
NCBI Official Symbol
PAF1
NCBI Official Synonym Symbols
20S PROTEASOME SUBUNIT PAF1; ARS5; ARSENIC TOLERANCE 5; ATPSM30; MJB21.17; MJB21_17; proteasome alpha subunit F1
NCBI Protein Information
proteasome alpha subunit F1
NCBI Summary
encodes a protein with extensive homology to the largest subunit of the multicatalytic proteinase complex (proteasome). Negatively regulates thiol biosynthesis and arsenic tolerance.
UniProt Synonym Gene Names
ARS5; PRC2A; PRS1; PSM30; AtPSM30
UniProt Protein Name
Proteasome subunit alpha type-1-A
UniProt Synonym Protein Names
20S proteasome alpha subunit F-1; Proteasome 30 kDa subunit; Proteasome component 2A; AtPSM30; Proteasome subunit alpha type-6; Protein ARSENIC TOLERANCE 5
UniProt Primary Accession #
P34066
UniProt Secondary Accession #
O81150; Q8LF69
UniProt Related Accession #
P34066
UniProt Comments
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Negatively regulates thiol biosynthesis and arsenic tolerance.