NCBI Accession #
NP_001119446.2
NCBI GenBank Nucleotide #
NM_001125974.2
NCBI Official Full Name
profilin
NCBI Official Symbol
PRF3
NCBI Official Synonym Symbols
MIK19.4; MIK19_4; PFN3; PROFILIN; profilin 3; PROFILIN 3
NCBI Protein Information
profilin
NCBI Summary
Encodes profilin3, a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton. Originally known as profilin5, and later named profilin3. Expressed in vegetative organs.
UniProt Synonym Gene Names
PRF3
UniProt Protein Name
Profilin-5
UniProt Primary Accession #
Q9FE63
UniProt Secondary Accession #
Q8H123; Q8H2C7; B3H795; C0Z2Z0
UniProt Related Accession #
Q9FE63
UniProt Comments
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG .