NCBI Accession #
                                                
                                                
                                                    NP_001105451.1                                                
                                             
                                                                                    
                                                                                    
                                                
                                                    NCBI GenBank Nucleotide #
                                                
                                                
                                                    NM_001111981.2                                                
                                             
                                                                                    
                                                                                    
                                                
                                                    NCBI Official Full Name
                                                
                                                
                                                    profilin-2                                                
                                             
                                                                                    
                                                
                                                    NCBI Official Symbol
                                                
                                                
                                                    prf2                                                
                                             
                                                                                    
                                                
                                                    NCBI Official Synonym Symbols
                                                
                                                
                                                    PRO2; Profilin-2; GRMZM2G109842                                                
                                             
                                                                                    
                                                
                                                    NCBI Protein Information
                                                
                                                
                                                    profilin-2                                                
                                             
                                                                                    
                                                                                    
                                                
                                                    UniProt Synonym Gene Names
                                                
                                                
                                                    PRF2                                                
                                             
                                                                                    
                                                
                                                    UniProt Protein Name
                                                
                                                
                                                    Profilin-2                                                
                                             
                                                                                    
                                                
                                                    UniProt Synonym Protein Names
                                                
                                                
                                                    Pollen allergen Zea m 12; ZmPRO2; Allergen: Zea m 12                                                
                                             
                                                                                    
                                                
                                                    UniProt Primary Accession #
                                                
                                                
                                                    P35082                                                
                                             
                                                                                    
                                                
                                                    UniProt Related Accession #
                                                
                                                
                                                    P35082                                                
                                             
                                                                                    
                                                
                                                    UniProt Comments
                                                
                                                
                                                    Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.MiscellaneousThe variability of the residues taking part of IgE-binding epitopes might be responsible of the difference in cross-reactivity among olive pollen cultivars, and between distantly related pollen species, leading to a variable range of allergy reactions among atopic patients.