NCBI Accession #
NP_850218.1
NCBI GenBank Nucleotide #
NM_179887.3
NCBI Official Full Name
phosphate 2
NCBI Official Symbol
PHO2
NCBI Official Synonym Symbols
ATUBC24; phosphate 2; T1B8.8; T1B8_8; UBC24; UBIQUITIN-CONJUGATING ENZYME 24
NCBI Protein Information
phosphate 2
NCBI Summary
Encodes a ubiquitin-conjugating E2 enzyme. UBC24 mRNA accumulation is suppressed by miR399f, miR399b and miR399c. Involved in phosphate starvation response and mediates degradation of PHO1 and PHT1s at endomembrane.
UniProt Protein Name
Probable ubiquitin-conjugating enzyme E2 24
UniProt Synonym Protein Names
AtPHO2
UniProt Primary Accession #
Q8VY10
UniProt Secondary Accession #
P93012; Q0WLN6; Q0WM96
UniProt Related Accession #
Q8VY10
UniProt Comments
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins . Mediates PHO1 degradation through multivesicular body-mediated vacuolar proteolysis in response to inorganic phosphate (Pi) availability (PubMed:22634761). Negatively regulates the protein abundance of PHF1 and PHT1s under Pi-sufficient conditions by facilitating the degradation of PHT1 proteins at the endomembrane (PubMed:24122829).