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Probable RNA helicase SDE3 (SDE3), Recombinant Protein
Cat: RP02406
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Probable RNA helicase SDE3 (SDE3) , partial
Product Gene Name
SDE3 recombinant protein
Product Synonym Gene Name
SDE3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
113,363 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Probable RNA helicase
NCBI/Uniprot Data
NCBI Accession #
NP_172037.1
NCBI GI #
15220521
NCBI GenBank Nucleotide #
NM_100425.4
NCBI GeneID
837047
NCBI Official Full Name
P-loop containing nucleoside triphosphate hydrolases superfamily protein
NCBI Official Symbol
SDE3
NCBI Official Synonym Symbols
SILENCING DEFECTIVE; T25N20.11; T25N20_11
NCBI Protein Information
P-loop containing nucleoside triphosphate hydrolases superfamily protein
NCBI Summary
Encodes a protein with similarity to RNA helicases. Mutants are defective in post-transcriptional gene silencing.
UniProt Gene Name
SDE3
UniProt Protein Name
Probable RNA helicase SDE3
UniProt Synonym Protein Names
Silencing defective protein 3
UniProt Primary Accession #
Q8GYD9
UniProt Secondary Accession #
Q94KS1; Q9LR48
UniProt Related Accession #
Q8GYD9
UniProt Comments
Probable RNA helicase required for post-transcriptional gene silencing (PTGS), a process that provides protection in plants against virus infection and can suppress expression of transgenes. Plays a central role in RNA interference (RNAi) process, a process that mediates mRNA destruction of translational repression. Required for the assembly of the RISC complex, a complex required for target RNA destruction or repression. May be required in the RISC assembly to unwind miRNAs, in the production of single-stranded miRNA from the double-stranded miRNA, a key step in RISC formation. Involved in the amplification of sense-PTGS (S-PTGS), leading to siRNA production. Required for the maintenance but not the initiation of tobacco rattle virus (TRV)-mediated silencing, probably by mediating/maintaining DNA methylation and chromatin-based transcriptional gene silencing at some genomic locations.
For research use only, not for clinical use.