NCBI Accession #
NP_177566.3
NCBI GenBank Nucleotide #
NM_106086.5
NCBI Official Full Name
purine biosynthesis 4
NCBI Official Symbol
PUR4
NCBI Official Synonym Symbols
F1O17.7; F1O17_7; purine biosynthesis 4
NCBI Protein Information
purine biosynthesis 4
NCBI Summary
Encodes formylglycinamidine ribonucleotide synthase an enzyme involved in de novo purine biosynthesis. PUR4 is localizes to the chloroplast and mitochondria. Loss of PUR4 function affects male but not female gametophyte development.
UniProt Gene Name
At1g74260
UniProt Synonym Gene Names
FGAM synthase; FGAMS; FGAR amidotransferase; FGAR-AT
UniProt Protein Name
Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial
UniProt Synonym Protein Names
Formylglycinamide ribonucleotide amidotransferase; FGAR amidotransferase; FGAR-AT; Formylglycinamide ribotide amidotransferase
UniProt Primary Accession #
Q9M8D3
UniProt Secondary Accession #
A9Y5J1; F4HTW2
UniProt Related Accession #
Q9M8D3
UniProt Comments
Essential to the male gametophyte development. Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.