Probable lysine-specific demethylase JMJ14 (JMJ14), Recombinant Protein
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Probable lysine-specific demethylase JMJ14 (JMJ14), Recombinant Protein

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Cat: RP04816
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Probable lysine-specific demethylase JMJ14 (JMJ14) , partial
Product Gene Name
JMJ14 recombinant protein
Product Synonym Gene Name
JMJ14
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
101,969 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Probable lysine-specific demethylase

NCBI/Uniprot Data

NCBI Accession #
NP_001031681.1
NCBI GI #
79325193
NCBI GenBank Nucleotide #
NM_001036604.1
NCBI GeneID
827788
NCBI Official Full Name
JUMONJI 14
NCBI Official Symbol
JMJ14
NCBI Official Synonym Symbols
F9F13.50; F9F13_50; JUMONJI 14; PKDM7B
NCBI Protein Information
JUMONJI 14
NCBI Summary
Encodes a histone H3K4 demethylase repressing floral transition.
UniProt Gene Name
JMJ14
UniProt Synonym Gene Names
JMJ4; PKDM7B
UniProt Protein Name
Probable lysine-specific demethylase JMJ14
UniProt Synonym Protein Names
Jumonji domain-containing protein 14; Jumonji domain-containing protein 4; Lysine-specific histone demethylase JMJ14; Protein JUMONJI 14
UniProt Primary Accession #
Q8GUI6
UniProt Secondary Accession #
Q9SUN9; F4JUW8
UniProt Related Accession #
Q8GUI6
UniProt Comments
Transcriptional repressor (PubMed:25578968). Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a higher activity for H3K4me3 and H3K4me2 than H3K4me1. No activity on H3K9me3/2, H3K36me3/2 and H3K27me3/2. Represses FT and TSF expression to inhibit the floral transition. Binds around the transcription start site of the FT locus. Involved in the DRM2-mediated maintenance of DNA methylation, but not required for the de novo DNA methylation. Required for demethylating histone H3K4me3 at the target of RNA silencing. Together with NAC051/NAC052 and NAC050, regulates gene expression and flowering time, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968).

For research use only, not for clinical use.