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Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9 (SUVH9), Recombinant Protein
Cat: RP05003
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9 (SUVH9) , partial
Product Gene Name
SUVH9 recombinant protein
Product Synonym Gene Name
SUVH9
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
72,174 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Histone-lysine N-methyltransferase family
NCBI/Uniprot Data
NCBI Accession #
NP_001031625.1
NCBI GI #
79325081
NCBI GenBank Nucleotide #
NM_001036548.2
NCBI GeneID
826978
NCBI Official Full Name
SU(VAR)3-9 homolog 9
NCBI Official Symbol
SUVH9
NCBI Official Synonym Symbols
SDG22; SET22; SETDOMAIN GROUP 22; SU(VAR)3-9 homolog 9; T6G15.10; T6G15_10
NCBI Protein Information
SU(VAR)3-9 homolog 9
NCBI Summary
Encodes a SU(VAR)3-9 homolog, a SET domain protein. Known SET domain proteins are involved in epigenetic control of gene expression and act as histone methyltransferases. There are 10 SUVH genes in Arabidopsis and members of this subfamily of the SET proteins have an additional conserved SRA domain. A plant line expressing an RNAi construct directed against this gene has reduced agrobacterium-mediated tumor formation.
UniProt Gene Name
SUVH9
UniProt Synonym Gene Names
SDG22; SET22; H3-K9-HMTase 9; Su(var)3-9 homolog protein 9
UniProt Protein Name
Histone-lysine N-methyltransferase family member SUVH9
UniProt Synonym Protein Names
Histone H3-K9 methyltransferase 9; H3-K9-HMTase 9; Protein SET DOMAIN GROUP 22; Suppressor of variegation 3-9 homolog protein 9; Su(var)3-9 homolog protein 9
UniProt Primary Accession #
Q9T0G7
UniProt Related Accession #
Q9T0G7
UniProt Comments
Histone methyltransferase family member that plays a role in gene silencing (PubMed:19043555, PubMed:24463519, PubMed:27171427). Together with MORC6 and SUVH2, regulates the silencing of some transposable elements (TEs) (PubMed:27171427). According to PubMed:19043555, the protein does not bind S-adenosyl-L-methionine and lacks methyltransferase activity. Instead, it may function downstream of DRM2 in RNA-directed DNA methylation, binding to methylated DNA and recruiting DNA-directed RNA polymerase V to chromatin (PubMed:24463519, PubMed:27171427).
For research use only, not for clinical use.