Probable histone H2AXa (Os03g0721900, LOC_Os03g51200), Recombinant Protein
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Probable histone H2AXa (Os03g0721900, LOC_Os03g51200), Recombinant Protein

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Cat: RP14183
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Oryza sativa subsp. japonica (Rice)
Datasheet:

Product Info

Full Product Name
Recombinant Oryza sativa subsp. japonica Probable histone H2AXa (Os03g0721900, LOC_Os03g51200)
Product Gene Name
Os03g0721900 recombinant protein
Product Synonym Gene Name
Os03g0721900; LOC_Os03g51200
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSSSQGGGGR GKAKTTKAVS RSSKAGLQFP VGRIARYLKA GKYAERVGAG APVYLSAVLE YLAAEVLELA GNAARDNKKN RIVPRHIQLA VRNDEELSRL LGTVTIAAGG VLPNIQQVLL PKKGGGKGDI GSASQEF
Sequence Positions
1-137, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
14,271 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
XP_015628892.1
NCBI GI #
1002249421
NCBI GenBank Nucleotide #
XM_015773406.1
NCBI GeneID
4333939
NCBI Official Full Name
probable histone H2AXa
NCBI Official Symbol
LOC4333939
NCBI Official Synonym Symbols
OsJ_011892
NCBI Protein Information
probable histone H2AXa
UniProt Gene Name
Os03g0721900
UniProt Protein Name
Probable histone H2AXa
UniProt Primary Accession #
Q8LLP5
UniProt Secondary Accession #
Q10DS3; A3AM70
UniProt Related Accession #
Q8LLP5
UniProt Comments
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation .

For research use only, not for clinical use.