Probable histone-arginine methyltransferase 1.4 (PRMT14), Recombinant Protein
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Probable histone-arginine methyltransferase 1.4 (PRMT14), Recombinant Protein

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Cat: RP06643
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Probable histone-arginine methyltransferase 1.4 (PRMT14) , partial
Product Gene Name
PRMT14 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
58,713 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Probable histone-arginine methyltransferase

NCBI/Uniprot Data

NCBI Accession #
NP_199713.2
NCBI GI #
30695591
NCBI GenBank Nucleotide #
NM_124279.5
NCBI GeneID
834961
NCBI Official Full Name
protein arginine methyltransferase 4A
NCBI Official Symbol
PRMT4A
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 4A; ATPRMT4A; K19E20.17; K19E20_17; protein arginine methyltransferase 4A
NCBI Protein Information
protein arginine methyltransferase 4A
NCBI Summary
Encodes a type I protein arginine methyltransferase. PRMT4a can catalyze the asymmetric dimethylation of arginines 2,17, and 26 on histone 3 and can also methylate myelin basic protein in vitro. Double mutants lacking PRMT4a and 4b have reduced levels of histone 3 methylated at R17. These double mutants flower late due to defects in the autonomous pathway and they have elevated levels of FLC transcripts.
UniProt Gene Name
PRMT14
UniProt Synonym Gene Names
CARM1B; PRMT4A; AtPRMT14; AtPRMT4A
UniProt Protein Name
Probable histone-arginine methyltransferase 1.4
UniProt Synonym Protein Names
Coactivator-associated methyltransferase 1B; Protein arginine N-methyltransferase 4A; AtPRMT4A
UniProt Primary Accession #
A3KPF2
UniProt Secondary Accession #
Q3E8E0; Q84WN5; Q9FI68
UniProt Related Accession #
A3KPF2
UniProt Comments
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation, methylates histone H3 and activates transcription via chromatin remodeling.

For research use only, not for clinical use.