NCBI Accession #
NP_188605.1
NCBI GenBank Nucleotide #
NM_112861.4
NCBI Official Full Name
branched-chain aminotransferase4
NCBI Official Symbol
BCAT4
NCBI Official Synonym Symbols
branched-chain aminotransferase4
NCBI Protein Information
branched-chain aminotransferase4
NCBI Summary
Belongs to the branched-chain amino acid aminotransferase gene family. Encodes a methionine-oxo-acid transaminase. Involved in the methionine chain elongation pathway that leads to the ultimate biosynthesis of methionine-derived glucosinolates.
UniProt Synonym Gene Names
Atbcat-4
UniProt Protein Name
Methionine aminotransferase BCAT4
UniProt Synonym Protein Names
Branched-chain-amino-acid aminotransferase 4; Atbcat-4; Methionine-oxo-acid transaminase BCAT4
UniProt Primary Accession #
Q9LE06
UniProt Secondary Accession #
Q0WW34
UniProt Related Accession #
Q9LE06
UniProt Comments
Converts 2-oxo acids to branched-chain amino acids. Shows activity with L-Leu, L-Ile and L-Val as amino donors and alpha-keto-glutarate as an amino acceptor, but no activity for D-isomers of Leu, Ile, Val, Asp, Glu or Ala. Acts on methionine and its derivatives and the corresponding 2-oxo acids. Catalyzes the initial deamination of methionine to 4-methylthio-2-oxobutyrate as well as the transamination of other typical intermediates of the methionine chain elongation pathway.