NCBI Accession #
NP_175386.2
NCBI GenBank Nucleotide #
NM_103851.3
NCBI Official Full Name
presequence protease 2
NCBI Official Symbol
PREP2
NCBI Official Synonym Symbols
ATPREP2; F14J22.13; F14J22_13; presequence protease 2
NCBI Protein Information
presequence protease 2
NCBI Summary
Zinc metalloprotease pitrilysin subfamily A. Signal peptide degrading enzyme targeted to mitochondria and chloroplasts. Expressed in flower, leaf and root. Not expressed in silique and shoot.
UniProt Synonym Gene Names
ZNMP2; AtPreP2; PreP 2; AtZnMP2
UniProt Protein Name
Presequence protease 2, chloroplastic/mitochondrial
UniProt Synonym Protein Names
Zinc metalloprotease 2; AtZnMP2
UniProt Primary Accession #
Q8VY06
UniProt Secondary Accession #
Q9FX91
UniProt Related Accession #
Q8VY06
UniProt Comments
ATP-independent protease that degrades both mitochondrial and chloroplastic transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.