NCBI Accession #
NP_198566.2
NCBI GenBank Nucleotide #
NM_123109.5
NCBI Official Full Name
gated outwardly-rectifying K+ channel
NCBI Official Symbol
GORK
NCBI Official Synonym Symbols
gated outwardly-rectifying K+ channel; MPA22.4; MPA22_4
NCBI Protein Information
gated outwardly-rectifying K+ channel
NCBI Summary
Encodes a guard cell outward potassium channel. Belongs to the Shaker family K+ channel. This family includes five groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500). Mutants have increased water consumption and limited stomatal closure in response to abscisic and jasmonic acids. It forms a heteromeric K(out) channels with SKOR. The gene is expressed ubiquitously in root and the vasculature and guard cells of leaves. Expression is suppressed during agrobacterium-induced tumor formation and increased in response to water deprivation and cold.
UniProt Synonym Gene Names
AtGORK
UniProt Protein Name
Potassium channel GORK
UniProt Synonym Protein Names
Guard cell outward rectifying K(+) channel; AtGORK
UniProt Primary Accession #
Q94A76
UniProt Secondary Accession #
Q9FNY5
UniProt Related Accession #
Q94A76
UniProt Comments
Major selective outward-rectifying potassium channel of the guard cell membrane. Involved in regulation of stomatal movements according to the water status. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization. Conductance of the channel is modulated in a potassium-dependent fashion. May interact with the cytoskeleton or with regulatory proteins.