Polycomb group protein VERNALIZATION 2 (VRN2), Recombinant Protein
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Polycomb group protein VERNALIZATION 2 (VRN2), Recombinant Protein

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Cat: RP02530
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Polycomb group protein VERNALIZATION 2 (VRN2)
Product Gene Name
VRN2 recombinant protein
Product Synonym Gene Name
VRN2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MCRQNCRAKS SPEEVISTDE NLLIYCKPVR LYNIFHLRSL GNPSFLPRCL NYKIGAKRKR KSRSTGMVVF NYKDCNNTLQ RTEVREDCSC PFCSMLCGSF KGLQFHLNSS HDLFEFEFKL LEEYQTVNVS VKLNSFIFEE EGSDDDKFEP FSLCSKPRKR RQRGGRNNTR RLKVCFLPLD SPSLANGTEN GIALLNDGNR GLGYPEATEL AGQFEMTSNI PPAIAHSSLD AGAKVILTTE AVVPATKTRK LSAERSEARS HLLLQKRQFY HSHRVQPMAL EQVMSDRDSE DEVDDDVADF EDRQMLDDFV DVNKDEKQFM HLWNSFVRKQ RVIADGHISW ACEVFSRFYE KELHCYSSLF WCWRLFLIKL WNHGLVDSAT INNCNTILEN CRNTSVTNNN NNSVDHPSDS NTNNNNIVDH PNDIKNKNNV DNKDNNSRDK
Sequence Positions
1-440, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
12,421 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Polycomb group protein

NCBI/Uniprot Data

NCBI Accession #
NP_567517.1
NCBI GI #
18414761
NCBI GenBank Nucleotide #
NM_117787.4
NCBI GeneID
827392
NCBI Official Full Name
VEFS-Box of polycomb protein
NCBI Official Symbol
VRN2
NCBI Official Synonym Symbols
REDUCED VERNALIZATION RESPONSE 2
NCBI Protein Information
VEFS-Box of polycomb protein
NCBI Summary
The VERNALIZATION2 (VRN2) gene mediates vernalization and encodes a nuclear-localized zinc finger protein with similarity to Polycomb group (PcG) proteins of plants and animals. In wild-type Arabidopsis, vernalization results in the stable reduction of the levels of the floral repressor FLC. In vrn2 mutants, FLC expression is downregulated normally in response to vernalization, but instead of remaining low, FLC mRNA levels increase when plants are returned to normal temperatures. VRN2 maintains FLC repression after a cold treatment, serving as a mechanism for the cellular memory of vernalization. Required for complete repression of FLC. Required for the methylation of histone H3
UniProt Gene Name
VRN2
UniProt Protein Name
Polycomb group protein VERNALIZATION 2
UniProt Primary Accession #
Q8W5B1
UniProt Secondary Accession #
O23524; O23525; Q8W5B2; Q94CF5
UniProt Related Accession #
Q8W5B1
UniProt Comments
Polycomb group (PcG) protein. Plays a central role in vernalization by maintaining repressed the homeotic gene FLC, a floral repressor, after a cold treatment. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Associates constitutively along the whole FLC locus.

For research use only, not for clinical use.