NCBI Accession #
O50017.1
NCBI Official Full Name
Poly
NCBI Official Symbol
LOC103635146
NCBI Official Synonym Symbols
PARP; Poly; PARP2; PARP-2; ADPRT-2; GRMZM2G099231; GRMZM2G124718
NCBI Protein Information
poly [ADP-ribose] polymerase 2
UniProt Synonym Gene Names
PARP; PARP-2; ADPRT-2
UniProt Protein Name
Poly [ADP-ribose] polymerase 2
UniProt Synonym Protein Names
NAD(+) ADP-ribosyltransferase 2; ADPRT-2; Poly[ADP-ribose] synthase 2
UniProt Primary Accession #
O50017
UniProt Related Accession #
O50017
UniProt Comments
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks .