NCBI Accession #
NP_176191.1
NCBI GenBank Nucleotide #
NM_104675.3
NCBI Official Full Name
aminophospholipid ATPase 3
NCBI Official Symbol
ALA3
NCBI Official Synonym Symbols
aminophospholipid ATPase 3; F23H11.14; F23H11_14
NCBI Protein Information
aminophospholipid ATPase 3
NCBI Summary
Encodes a phospholipid translocase. Involved in secretory vesicle formation from trans-Golgi in peripheral columella cells at the root tip. Mutants have short primary roots and grow slower.
UniProt Synonym Gene Names
AtALA3
UniProt Protein Name
Phospholipid-transporting ATPase 3
UniProt Synonym Protein Names
Aminophospholipid ATPase 3
UniProt Primary Accession #
Q9XIE6
UniProt Secondary Accession #
Q8RWQ3
UniProt Related Accession #
Q9XIE6
UniProt Comments
Involved in transport of phospholipids. Contributes to transmembrane flipping of lipids. Required for secretory processes during plant development. Requires an interaction with an ALIS protein for activity. Has activity with phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine, but not with lysolipid (PubMed:18344284, PubMed:19566596, PubMed:20053675). Modifies endomembranes in multiple cell types, enabling structural changes, or signaling functions that are critical for normal development and adaptation to varied growth environments (PubMed:23667493).