NCBI Accession #
NP_001318645.1
NCBI GenBank Nucleotide #
NM_001343920.1
NCBI Official Full Name
phospholipase D alpha 3
NCBI Official Symbol
PLDALPHA3
NCBI Official Synonym Symbols
F18G18.110; F18G18_110; phospholipase D alpha 3
NCBI Protein Information
phospholipase D alpha 3
NCBI Summary
member of C2-PLD subfamily. Analyses on the gene structures/sequences, overall amino acid sequences, and domain structures indicate that PLDalpha3 is most closely related to other two PLDalphas than to other PLDs. Phylogenetic analysis has not identified a true ortholog for PLDalpha3. Involved in hyperosmotic response.
UniProt Gene Name
PLDALPHA3
UniProt Synonym Gene Names
PLD alpha 3
UniProt Protein Name
Phospholipase D alpha 3
UniProt Primary Accession #
P58766
UniProt Related Accession #
P58766
UniProt Comments
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA) (PubMed:18364466). Active with phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and phosphatidylserine (PS) as substrates (PubMed:18364466). No activity toward phosphatidylinositol (PI) or PIP2 (PubMed:18364466). Positively mediates plant responses to hyperosmotic stresses and promotes root growth, flowering, and stress avoidance (PubMed:18364466, PubMed:19704505). Not involved in the abscisic acid regulation of stomatal movement and transpirational water loss (PubMed:18364466).