NCBI Accession #
NP_187214.2
NCBI GenBank Nucleotide #
NM_111436.6
NCBI Official Full Name
phospholipase D P2
NCBI Official Symbol
PLDP2
NCBI Official Synonym Symbols
F18C1.10; F18C1_10; PDLZ2; PHOSPHOLIPASE D; phospholipase D P2; PHOSPHOLIPASE D ZETA 2; PLDZETA2
NCBI Protein Information
phospholipase D P2
NCBI Summary
Encodes a member of the PXPH-PLD subfamily of phospholipase D proteins. Regulates vesicle trafficking. Required for auxin transport and distribution and hence auxin responses. This subfamily is novel structurally different from the majority of plant PLDs by having phox homology (PX) and pleckstrin homology (PH) domains. Involved regulating root development in response to nutrient limitation. Plays a major role in phosphatidic acid production during phosphate deprivation. Induced upon Pi starvation in both shoots and roots. Involved in hydrolyzing phosphatidylcholine and phosphatidylethanolamine to produce diacylglycerol for digalactosyldiacylglycerol synthesis and free Pi to sustain other Pi-requiring processes. Does not appear to be involved in root hair patterning. Expression is upregulated in the shoot of cax1/cax3 mutant.
UniProt Gene Name
PLPZETA2
UniProt Synonym Gene Names
AtPLDp2
UniProt Protein Name
Phospholipase D zeta 2
UniProt Synonym Protein Names
Phospholipase D p2; AtPLDp2; Phospholipase D2 PHOX and PX-containing domain protein
UniProt Primary Accession #
Q9M9W8
UniProt Secondary Accession #
Q7XZQ3; A3KH17
UniProt Related Accession #
Q9M9W8
UniProt Comments
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Phosphatidylcholine-selective (PubMed:11891260). Regulates vesicle trafficking and auxin responses (PubMed:17259265). Required for the normal cycling of PIN-2 containing vesicles (PubMed:17259265). Contributes to the supply of inorganic phosphorus for cell metabolism and diacylglycerol moieties for galactolipid synthesis in phosphorus-starved roots (PubMed:16891548, PubMed:16617110). Involved in root elongation during phosphate limitation (PubMed:16384909).